Research progress in characteristics of B cells in high-, low- and non-responsive individuals after HBV vaccination / 中华微生物学和免疫学杂志
Chinese Journal of Microbiology and Immunology
; (12): 159-164, 2021.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-885652
Responsible library:
WPRO
ABSTRACT
Hepatitis B virus (HBV) infection remains a serious global health problem, which can lead to acute and chronic liver diseases and a variety of complications. HBV vaccination, which induces B cells to secrete protective hepatitis B surface antibody (HBsAb), is an important measure to prevent HBV infection. Some studies have shown that different individuals have different responses to HBV vaccine, which can be divided into ultra-high/high, normal/medium and low/non-response. Research on the potential mechanisms can provide reference for the preparation of high-titer HBsAb and the prevention and treatment of HBV infection. This paper reviewed the research situation and progress in the characteristics and mechanism of B cells in different responders after HBV vaccination.
Full text:
Available
Health context:
SDG3 - Health and Well-Being
Health problem:
Target 3.8 Achieve universal access to health
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Microbiology and Immunology
Year:
2021
Document type:
Article