Genotype distribution of Porphyromonas gingivalis among smokers / 대한구강보건학회지

ABSTRACT

Objectives@#The purpose of this study was to determine the difference in the genotype distribution of Porphyromonas gingivalis (P. gingivalis), the main cause of periodontal disease, according to smoking status. @*Methods@#Two hundred thirty adults with periodontal disease were selected as subjects and were classified into either a smoking or non-smoking group. Smoking behavior was assessed with a self-administered questionnaire, and subgingival plaque was collected and analyzed using polymerase chain reaction to confirm the P. gingivalis genotype. For statistical analysis, SPSS Ver 25.0 was used. @*Results@#P. gingivalis was expressed in 224 subjects (97.4%), and there was no difference in its expression rate according to smoking. However, there was a significant difference in smoking in type III genotype and smoking period in type II genotype with P. gingivalis (P=0.003). @*Conclusions@#Although smoking was not related to the overall distribution of P. gingivalis, increased volume and duration may inhibit the expression of type II and type III genotypes.