Anti-Mullerian hormone levels as a predictor of clinical pregnancy in in vitro fertilization/intracytoplasmic sperm injection-embryo transfer cycles in patients over 40 years of age / 대한생식의학회지
Clinical and Experimental Reproductive Medicine
; : 143-148, 2015.
Article
in En
| WPRIM
| ID: wpr-91719
Responsible library:
WPRO
ABSTRACT
OBJECTIVE: The aim of the current study was to determine the predictive value of anti-Mullerian hormone (AMH) levels for pregnancy outcomes in patients over 40 years of age who underwent in vitro fertilization or intracytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET) cycles. METHODS: We retrospectively analyzed the medical records of 188 women aged 40 to 44 years who underwent IVF/ICSI-fresh ET cycles due to unexplained infertility in the fertility center of CHA Gangnam Medical Center. Patients were divided into group A, with AMH levels or =1.0 ng/mL (n=91). We compared the clinical pregnancy rate (CPR) in the two groups and performed logistic regression analysis to identify factors that had a significant effect on the CPR. RESULTS: The CPR was significantly lower in group A than group B (7.2% vs. 24.2%, p or =1.90 ng/mL than in the group with AMH levels <1.90 ng/mL (p<0.001). CONCLUSION: Our study showed that AMH levels were predictive of clinical pregnancy in infertility patients over 40 years of age. Further prospective studies should be conducted to validate the predictive capability of AMH levels for the outcome of clinical pregnancy.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Spermatozoa
/
Pregnancy Outcome
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Fertilization in Vitro
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Logistic Models
/
Medical Records
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Prospective Studies
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Retrospective Studies
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ROC Curve
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Cardiopulmonary Resuscitation
/
Pregnancy Rate
Type of study:
Observational_studies
/
Prognostic_studies
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Risk_factors_studies
Limits:
Female
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Humans
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Pregnancy
Language:
En
Journal:
Clinical and Experimental Reproductive Medicine
Year:
2015
Document type:
Article