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Recent Perspective on Thiazolidinedione / 임상당뇨병
Article in Korean | WPRIM (Western Pacific) | ID: wpr-918914
Responsible library: WPRO
ABSTRACT
Thiazolidinedione (TZD) is an insulin sensitizer that improves insulin resistance in the adipose tissue, liver, and muscles and has a pancreas-protective effect while inhibiting gluconeogenesis. Its other advantages include a glucose lowering effect, its durability, cardiovascular benefit, and recent evidence in nonalcoholic fatty liver disease and dementia. However, there are also concerns about fluid retention/edema/heart failure, bladder cancer, and fractures with TZD use. TZD can still be a useful option for diabetes treatment when calculating risk versus benefit, but appropriate selection of patients is needed.
Full text: Available Database: WPRIM (Western Pacific) Language: Korean Journal: Journal of Korean Diabetes Year: 2021 Document type: Article
Full text: Available Database: WPRIM (Western Pacific) Language: Korean Journal: Journal of Korean Diabetes Year: 2021 Document type: Article
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