Progress of Immune Checkpoint Inhibitors
in the Treatment of Advanced Pulmonary Neuroendocrine Tumors / 中国肺癌杂志
Chinese Journal of Lung Cancer
; (12): 784-789, 2021.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-922147
Responsible library:
WPRO
ABSTRACT
Pulmonary neuroendocrine tumors (PNETs) are a kind of epithelial tumors originating from pulmonary neuroendocrine cells, accounting for about 20% of primary lung tumors, including typical carcinoid, atypical carcinoid, small cell carcinoma, and large cell neuroendocrine carcinoma. The morphologic and clinical characteristics of these four types of PNETs are relatively highly heterogeneous. Immune checkpoint inhibitors (ICIs) have been shown robust antitumor activity in a variety of solid tumors. Treatment regimens of advanced PNETs have developed greatly in the past decade, but ICIs are still in their infancy in the field of PNETs. This review focuses on the landscape of current clinical trials and research as well as the situation of ICIs-related biomarkers in PNETs.
.
Full text:
Available
Health context:
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
Health problem:
Other Respiratory Diseases
/
Trachea, Bronchus, Lung Cancers
Database:
WPRIM (Western Pacific)
Main subject:
Carcinoid Tumor
/
Neuroendocrine Tumors
/
Neuroectodermal Tumors, Primitive
/
Carcinoma, Neuroendocrine
/
Immune Checkpoint Inhibitors
/
Lung Neoplasms
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Lung Cancer
Year:
2021
Document type:
Article