Rescue of male infertility through correcting a genetic mutation causing meiotic arrest in spermatogonial stem cells / 亚洲男科学杂志(英文版)
Asian Journal of Andrology
; (6): 590-599, 2021.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-922360
Responsible library:
WPRO
ABSTRACT
Azoospermia patients who carry a monogenetic mutation that causes meiotic arrest may have their biological child through genetic correction in spermatogonial stem cells (SSCs). However, such therapy for infertility has not been experimentally investigated yet. In this study, a mouse model with an X-linked testis-expressed 11 (TEX11) mutation (Tex11
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Spermatogenesis
/
Azoospermia
/
Adult Germline Stem Cells
/
Infertility, Male
/
Mutation
Limits:
Animals
Language:
English
Journal:
Asian Journal of Andrology
Year:
2021
Document type:
Article
