Ultrasound-Guided Continuous Thoracic Paravertebral Block Improves Patient's Quality of Recovery After Open Hepatectomy: A Randomized, Double-Blind, Placebo-Controlled Trial / 中国医学科学杂志(英文版)
Chinese Medical Sciences Journal
; (4): 15-22, 2022.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-928244
Responsible library:
WPRO
ABSTRACT
Background Ultrasound-guided continuous thoracic paravertebral block can provide pain-relieving and opioid-sparing effects in patients receiving open hepatectomy. We hypothesize that these effects may improve the quality of recovery (QoR) after open hepatectomy. Methods Seventy-six patients undergoing open hepatectomy were randomized to receive a continuous thoracic paravertebral block with ropivacaine (CTPVB group) or normal saline (control group). All patients received patient-controlled intravenous analgesia with morphine postoperatively for 48 hours. The primary outcome was the global Chinese 15-item Quality of Recovery score on postoperative day 7, which was statistically analyzed using Student's t-test. Results Thirty-six patients in the CTPVB group and 37 in the control group completed the study. Compared to the control group, the CTPVB group had significantly increased global Chinese 15-item Quality of Recovery scores (133.14 ± 12.97 vs. 122.62 ± 14.89, P = 0.002) on postoperative day 7. Postoperative pain scores and cumulative morphine consumption were significantly lower for up to 8 and 48 hours (P < 0.05; P = 0.002), respectively, in the CTPVB group. Conclusion Perioperative CTPVB markably promotes patient's QoR after open hepatectomy with a profound analgesic effect in the early postoperative period.
Full text:
Available
Health context:
SDG3 -Target 3.5 Prevention and treatment of consumption of psychoactive substances
Health problem:
Opioid Abuse
Database:
WPRIM (Western Pacific)
Main subject:
Pain, Postoperative
/
Pain Measurement
/
Double-Blind Method
/
Ultrasonography, Interventional
/
Hepatectomy
/
Anesthetics, Local
/
Morphine
Type of study:
Controlled clinical trial
Limits:
Humans
Language:
English
Journal:
Chinese Medical Sciences Journal
Year:
2022
Document type:
Article