Research progress of silk fibroin-based nanoparticulate drug delivery systems / 药学学报
Acta Pharmaceutica Sinica
; (12): 1792-1800, 2022.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-929421
Responsible library:
WPRO
ABSTRACT
Silk fibroin is a natural polymer with certain water solubility, structural modification, good biocompatibility and biodegradability, which can be used as a drug delivery carrier material. As a promising drug delivery system, drug-loaded silk fibroin nanoparticles can control drug release, reduce toxicity and improve therapeutic effects. In this paper, the basic characteristics of silk fibroin, the preparation methods of drug-loaded silk fibroin nanoparticles and the application of silk fibroin in nanoparticulate drug delivery systems are reviewed, and on this basis, the further development of drug-loaded silk fibroin nanoparticles is prospected.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Acta Pharmaceutica Sinica
Year:
2022
Document type:
Article