Advance in diagnosis and treatment of drug-resistant tuberculosis in children / 国际儿科学杂志

ABSTRACT

Tuberculosis is one of the infectious diseases with high mortality throughout the world, and drug-resistant tuberculosis in particular aggravates the global burden of disease.As a special group of tuberculosis patients, children have great difficulties in the diagnosis and treatment of diseases due to atypical clinical symptoms, difficulty in collecting test samples, and low bacterial load of samples.In recent years, based on medical evidence, many new detection techniques and drug treatment protocols for drug resistant tuberculosis have emerged, but there is still a lack of child-related clinical data and guideline consensus.The incidence of tuberculosis in children affects the number of adult tuberculosis patients in the future, and it is important to pay attention to tuberculosis in children for disease control, while for tuberculosis patients in children, rapid and correct diagnosis and early rational treatment are crucial.This article reviews the latest advance in the diagnosis and treatment of drug-resistant tuberculosis in children based on the available evidence.