Appropriate Use of Glycopeptide Antibiotics and Therapeutic Drug Monitoring for Invasive Infections / 대한내과학회지
Korean Journal of Medicine
; : 463-477, 2021.
Article
in Korean
| WPRIM (Western Pacific)
| ID: wpr-938646
Responsible library:
WPRO
ABSTRACT
Vancomycin and teicoplanin are representative glycopeptide antibiotics with activities against gram-positive cocci. The area under the drug concentration–time curve (AUC)/minimal inhibitory concentration (MIC) has been extensively used as an indicator of the bacteriological response to glycopeptide antibiotics, and the trough concentration has been used as a surrogate marker for the AUC/MIC. However, the guidelines for therapeutic drug monitoring (TDM) are being revised in accordance with increasing pharmacokinetic understanding of glycopeptide antibiotics. This review describes the pharmacokinetic/pharmacodynamic characteristics of glycopeptide antibiotics and discusses their optimal use with appropriate TDM.
Full text:
Available
Database:
WPRIM (Western Pacific)
Type of study:
Practice guideline
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2021
Document type:
Article