Mobola plum seed methanolic extracts exhibit mixed type inhibition of angiotensin -converting enzyme in vitro
Asian Pacific Journal of Tropical Biomedicine
; (12): 1079-1084, 2017.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-950490
Responsible library:
WPRO
ABSTRACT
Objective To explore the possible inhibitory potentials and mechanism by Mobola plum (Parinari curatellifolia) seeds crude methanol (CE) and flavonoid-rich (FE) extracts on angiotensin-1-converting enzyme (ACE ). Methods The sensitivity and kinetic model of inhibition of CE and FE on ACE using N-[3-(2-furyl)-acryloyl]-Phe-Gly-Gly as enzyme substrate for ACE was evaluated by Michealis Menten approach. The inhibition mechanism was explored from Lineweaver–Burk model and IC
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Asian Pacific Journal of Tropical Biomedicine
Year:
2017
Document type:
Article