Research progress on the effect mechanism of polysaccharides against pancreatic cancer / 中国药房
China Pharmacy
; (12): 111-116, 2023.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-953729
Responsible library:
WPRO
ABSTRACT
Polysaccharide is a recognized immunomodulator that has been shown to have inhibitory effects on a variety of cancer cells and has the potential to be developed as an anti-cancer drug. Pancreatic cancer, one of the cancers with the highest mortality rate, is treated with long-term chemotherapeutic drugs and is prone to a variety of side effects such as immune deficiency, fatigue, and neurological lesions. The polysaccharide anti-pancreatic cancer research landscape both domestically and internationally is summarized in this publication. By regulating nuclear factor-κB, Hippo-Yes-associated protein, integrin and other signaling pathways, polysaccharide components play an anti-pancreatic cancer role by multi-target ways, such as inducing apoptosis and autophagy, inhibiting proliferation, migration and invasion of cancer cells, and regulating the cancer cell cycle.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2023
Document type:
Article