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Current status and prospect of biomarker research for schizophrenia / 中华检验医学杂志
Article in Chinese | WPRIM (Western Pacific) | ID: wpr-958642
Responsible library: WPRO
ABSTRACT
Schizophrenia is a serious mental disease. The diagnosis of schizophrenia so far relies heavily on subjective evidence, including self-reported experiences by patients, manifestations described by relatives, and abnormal behaviors assessed by psychiatrists. The diagnosis, monitoring of the disease progression and therapy efficacy assessment are challenging due to the lack of established laboratory biomarkers. Based on the current literature, clinical consensus, guidelines, and expert recommendations, this review highlighted evidence-based potential laboratory biomarkers for the diagnosis of schizophrenia, including genetic biomarkers, neurotransmitters, neurodevelopmental-related proteins, and intestinal flora, and discussed the potential future directions for the application of these biomarkers in this field, aiming to provide an objective basis for the use of these biomarkers in the early and accurate diagnosis, treatment, and prognosis and rehabilitation assessment of schizophrenia.

Full text: Available Database: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Laboratory Medicine Year: 2022 Document type: Article
Full text: Available Database: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Laboratory Medicine Year: 2022 Document type: Article
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