Cryptorchidism is a useful clue for Idiopathic Hypogonadotropic Hypogonadism in Pituitary Stalk Thickening / Journal of the ASEAN Federation of Endocrine Societies
Journal of the ASEAN Federation of Endocrine Societies
; : 95-97, 2021.
Article
in English
| WPRIM (Western Pacific)
| ID: wpr-961974
Responsible library:
WPRO
ABSTRACT
@#Pituitary stalk lesions can represent a wide range of pathologies. The exact cause is often unknown due to hesitancy to proceed with biopsy. We present a 16-year-old adolescent who presented with delayed puberty, short stature and bilateral cryptorchidism. He was found to have a thickened pituitary stalk of uncertain etiology with partial hypopituitarism (gonadotrophin and growth hormone deficiency) on further assessment. The presence of bilateral cryptorchidism and micropenis represents lack of “mini puberty,” a phenomenon of activation of the hypothalamic-pituitary-gonadal (HPG) axis in-utero or within the first few months of life.1 These key clinical features have been useful to establish an early temporal relationship and suggest a congenital origin of disease. This enabled a more conservative approach of surveillance to be employed as opposed to invasive pathological examination with pituitary stalk biopsy.
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Database:
WPRIM (Western Pacific)
Main subject:
Pituitary Diseases
/
Growth Hormone
/
Cryptorchidism
/
Hypopituitarism
Language:
English
Journal:
Journal of the ASEAN Federation of Endocrine Societies
Year:
2021
Document type:
Article