Diflucortolone Valerate 0.3% - new potent topical corticosteroid with increased margin

ABSTRACT

Diflucortolone valerate has been made available in a 0.3% concentration as a very potent preparation for treatment of corticosteroid-responsive problem dermatoses It was found to combine pronounced clinical efficacy with a comparatively better tolerance in pharmacological test models These favourable features were confirmed in an open clinical trial in the Philippines involving 143 patients mostly with more severe chronic recurrent and resistant skin diseases Diflucortolone valerate 0.3% therefore appears to be a topical corticosteroid preparation of choice, when a very potent preparation is needed for initiation of treatment in severe cort costeroid-responsive skin diseases.(Author)