Strategy and challenge of innovative drug research and development from clinically effective ingredients of traditional Chinese medicine / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 1705-1710, 2023.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-981387
Responsible library:
WPRO
ABSTRACT
Novel drug discovery from the active ingredients of traditional Chinese medicine is the most distinctive feature and advantageous field of China, which has provided an unprecedented opportunity. However, there are still problems such as unclear functional substance basis, action targets and mechanism, which greatly hinder the clinical transformation of active ingredients in traditional Chinese medicine. Based on the analysis of the current status and progress of innovative drug research and development in China, this paper aimed to explore the prospect and difficulties of the development of natural active ingredients from traditional Chinese medicine, and to explore the efficient discovery of trace active ingredients in traditional Chinese medicine, and obtain drug candidates with novel chemical structure, unique target/mechanism and independent intellectual property rights, in order to provide a new strategy and a new model for the development of natural medicine with Chinese characteristics.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Research
/
Drugs, Chinese Herbal
/
China
/
Drug Discovery
/
Medicine, Chinese Traditional
Country/Region as subject:
Asia
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2023
Document type:
Article