Cell apoptosis in closed cerebellar contusion in rat / 法医学杂志
Journal of Forensic Medicine
; (6): 74-77, 2002.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-982932
Responsible library:
WPRO
ABSTRACT
OBJECTIVE@#To observe the cell apoptosis explore closed cerebellar contusion in rat.@*METHODS@#SD rats model of contusion was established and apototic cells were detected by TUNEL method at 5, 10, 30, 45, 60 min and 2, 4, 6, 8, 12 h, after injury.@*RESULTS@#Apototic cells in contusion area appeared at 1 h after closed cerebellar contusion, reached the peak at 4-6 h, then decreased and so as marginal area where the peak was in 6-8 h.@*CONCLUSION@#The apoptotic index of closed contusion of cerebellum in different injury time may provide a new sensitive and objective method for the forensic early injury time estimation.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Time Factors
/
Brain Injuries
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Cerebellum
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Rats, Sprague-Dawley
/
Apoptosis
/
In Situ Nick-End Labeling
Limits:
Animals
Language:
Chinese
Journal:
Journal of Forensic Medicine
Year:
2002
Document type:
Article