Immunohistochemical observation of heart-type fatty acid binding-protein in early myocardial ischemia / 法医学杂志
Journal of Forensic Medicine
; (6): 15-17, 2004.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-983009
Responsible library:
WPRO
ABSTRACT
OBJECTIVE@#The sensitivity of heart-type fatty acid binding-protein (H-FABP) in the postmortem diagnosis of myocardial ischemia was explored.@*METHODS@#The changes of H-FABP staining in normal, infarcted and suspected ischemia of myocardial cells were studied by immunohistochemistry.@*RESULTS@#There was no depletion in normal control group, and obvious depletion was observed in myocardial infarcted group. Among 9 suspected myocardial ischemia group, 3 cases showed obvious depletion and 3 cases showed vague depletion for H-FABP, there were obvious depletion of Mb in 4 suspected myocardial ischemia cases and vague depletion in 2 cases for Mb. It is indicated that H-FABP can be used to diagnose early myocardial ischemia.@*CONCLUSION@#H-FABP is quite sensitive and useful for the diagnosis of early myocardial ischemia.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Enzyme-Linked Immunosorbent Assay
/
Immunohistochemistry
/
Biomarkers
/
Carrier Proteins
/
Sensitivity and Specificity
/
Myocardial Ischemia
/
Creatine Kinase
/
Fatty Acid-Binding Proteins
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Myocardium
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Myoglobin
Limits:
Humans
Language:
Chinese
Journal:
Journal of Forensic Medicine
Year:
2004
Document type:
Article