Study on determination and distribution of GHB in biological fluids and tissues of acute poisoned rats / 法医学杂志
Journal of Forensic Medicine
; (6): 55-57, 2006.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-983131
Responsible library:
WPRO
ABSTRACT
OBJECTIVE@#e To investigate the distribution of GHB in biological fluids and tissues and provide methodand information for detcetion of GHB in Biological Fluids and Tissues METHOD The concentrations of GHB in Biological Fluids and Tissues were analyzed by gas chromatography-mass spectrometry; Two groups of rats were fed with 1000 mg/kg of GHB and were killed at 1 hour and 3 hours post dose, respectively. RESULTS GHB concentrations of the administrated groups distributed in a degressive order of urine, stomach, blood, intestine, kidney, lung, spleen, heart, liver and brain.@*CONCLUSION@#Urine was the best specimen for the determination of GHB concentrations in biological fluids and tissues.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Tissue Distribution
/
Random Allocation
/
Substance Abuse Detection
/
Acute Disease
/
Administration, Oral
/
Rats, Sprague-Dawley
/
Gastric Mucosa
/
Hydroxybutyrates
/
Kidney
/
Lung
Limits:
Animals
Language:
Chinese
Journal:
Journal of Forensic Medicine
Year:
2006
Document type:
Article