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Dissection of cavernous nerves in rat and model of neurological erectile dysfunction / 法医学杂志
Journal of Forensic Medicine ; (6): 183-185, 2006.
Article in Chinese | WPRIM (Western Pacific) | ID: wpr-983175
Responsible library: WPRO
ABSTRACT
OBJECTIVES@#To identify rat cavernous nerve and establish a rat model of erectile dysfunction caused by injury of cavernous nerve.@*METHODS@#Ten rats were undergone dissections. 30 experimental rats were randomized into 2 groups, cavernous nerve were identified by electrical stimulation. One month after surgery, rat models were evaluated by electrical stimulation.@*RESULTS@#The anatomic structure of cavernous nerve in rats are highly similar to human beings, the erection can be evoked by stimulating cavernous nerves, and after cavernous nerve injury it can not be evoked (P < 0.05).@*CONCLUSION@#Because of the highly similarity of cavernous nerve between rats and human beings, so as the suitable price, rat should be used as the ideal ED experimental animal. The model of ED caused by cavernous nerve injury is reliable.
Subject(s)
Full text: Available Database: WPRIM (Western Pacific) Main subject: Penis / Rats, Sprague-Dawley / Disease Models, Animal / Electric Stimulation / Ganglia, Autonomic / Erectile Dysfunction Limits: Animals Language: Chinese Journal: Journal of Forensic Medicine Year: 2006 Document type: Article
Full text: Available Database: WPRIM (Western Pacific) Main subject: Penis / Rats, Sprague-Dawley / Disease Models, Animal / Electric Stimulation / Ganglia, Autonomic / Erectile Dysfunction Limits: Animals Language: Chinese Journal: Journal of Forensic Medicine Year: 2006 Document type: Article
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