Polymorphism of five short tandem repeat systems in Chinese Han population in Chengdu / 法医学杂志
Journal of Forensic Medicine
; (6): 338-341, 2007.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-983314
Responsible library:
WPRO
ABSTRACT
OBJECTIVE@#To obtain population genetic data of loci D11S4951, D11S4957, GATA193H05, D2S2951, and D6S2421 in Han population in Chengdu area and to validate the value of their forensic application.@*METHODS@#Blood samples were collected in EDTA tubes from unrelated individuals. DNAs were extracted with Chelex-100 and were analyzed by PCR and horizontal PAGE followed by silver staining.@*RESULTS@#Alleles 7, 10, 8, 6 and 8 were found in 5 STR loci, respectively. No deviations from Hardy-Weinberg balance were observed. The heterozygosities observed were 0.743, 0.772, 0.833, 0.650 and 0.800, respectively. The chances of exclusion were 0.497, 0.549, 0.662, 0.356 and 0.599, and the discrimination powers were 0.863, 0.912, 0.947, 0.829 and 0.931.@*CONCLUSION@#All of the five loci studied may be useful markers for individual identification and paternity testing.
Full text:
Available
Database:
WPRIM (Western Pacific)
Main subject:
Polymorphism, Genetic
/
Rape
/
Genetic Markers
/
China
/
Polymerase Chain Reaction
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Tandem Repeat Sequences
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Asian People
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Electrophoresis, Polyacrylamide Gel
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Alleles
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Forensic Medicine
Limits:
Humans
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Journal of Forensic Medicine
Year:
2007
Document type:
Article