Progress in pathogenesis of perinatal group B streptococcal infection / 中华围产医学杂志
Chinese Journal of Perinatal Medicine
; (12): 919-924, 2022.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-995037
Responsible library:
WPRO
ABSTRACT
Group B Streptococcus (GBS) is a major cause of severe perinatal infection, stillbirth, premature delivery, and neonatal infectious diseases. Ascending infection after vaginal colonization is the main route of prenatal GBS transmission. The pathogenic mechanism of GBS from asymptomatic colonization to invasive infection mainly relates to virulence factors, the regulation of two-component systems and immune escape. This paper reviews progress in pathogenic mechanism of perinatal GBS infection in recent years, aiming to provide a theoretical basis for the development of vaccines and new treatment approaches against GBS.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Perinatal Medicine
Year:
2022
Document type:
Article