A bladder sparing approach in a case of prostate Rhabdomyosarcoma with bladder extension in a one-year old male

ABSTRACT

@#Rhabdomyosarcoma (RMS) is a malignantneoplasm of the skeletal muscle. Skeletal musclescan be found in all parts of the human body andthus such type of tumor occurs in almost any partof the body.1 In the pediatrics. It is the mostcommon soft tissue sarcoma and the third mostcommon solid tumor among pediatric patients. Inreport in the United States, on 350 cases, 15 to 20percent of this type of tumor were found in thegenitourinary system, and only 5 to 10 percentwere found in the bladder and prostate.2 With theadvent of multimodality treatment approach,patients with RMS of the bladder/prostate had asignificant improvement in terms of survival overthe past 30 years.This report presents a treatment strategy inwhich an initial unresectable tumor was managedwith neoadjuvant chemotherapy followed byorgan preservation surgery. This is the firstreported case at this institution of a one year oldwho had prostate rhabdomyosarcoma withbladder extension treated with neoadjuvantchemotherapy followed by bladder preservationsurgery.The study aimed to report a case of prostaterhabdomyosarcoma with bladder invasion in a pediatric patient, and describe the managementapproach, bladder preservation, and follow-up.