Plasma rich in growth factors (PRGF) in non-surgical periodontal therapy: a randomized clinical trial
Braz. oral res. (Online)
; 34: e034, 2020. tab, graf
Artículo
en Inglés
| LILACS, BBO - Odontología
| ID: biblio-1100933
Biblioteca responsable:
BR1.1
ABSTRACT
Abstract The aim of this split mouth, double blinded, randomized clinical trial was to evaluate the clinical efficacy of use of Plasma rich in growth factors (PRGF) as an adjunct to scaling and root planing (SRP) in the treatment of periodontal pockets. Twenty six patients (15 males, 11 females) diagnosed with generalized periodontitis with Pocket Depth > 5mm and plaque index score < 1.5, were randomly allocated by using computer generated random sequence, into two groups, one treated with intra-pocket application of PRGF adjunct to SRP and other with SRP alone. The clinical outcomes like pocket depth (PD), relative attachment level (RAL) and sulcus bleeding index (SBI) were assessed at baseline, 3 months and 6 months. Twenty two patients (44 sites) were analyzed at the end of 6 month follow-up, using SPSS 20.0v software. There was a significant statistical difference observed between both the groups favouring SRP +PRGF group in terms of PD (p = 0.007) and RAL (p = 0.021) at the end of 6 month follow-up. Also there was a statistical significant difference (< 0.001) at all time points compared to baseline, for all parameters in intra-group comparison. Moreover, the sites with PD>4mm necessitating further treatment after 6-month follow-up were significantly lesser for SRP+PRGF group. The use of PRGF technology in non-surgical periodontal therapy, by single intra-pocket application in to periodontal pockets as an adjunct to SRP, in chronic periodontitis patients, was found to be effective in reduction of pocket depth and gain in clinical attachment level.
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
BBO - Odontología
/
LILACS
Asunto principal:
Bolsa Periodontal
/
Raspado Dental
/
Péptidos y Proteínas de Señalización Intercelular
/
Plasma Rico en Plaquetas
Tipo de estudio:
Ensayo clínico controlado
/
Estudio observacional
/
Estudio pronóstico
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Braz. oral res. (Online)
Asunto de la revista:
Odontología
Año:
2020
Tipo del documento:
Artículo
País de afiliación:
India
/
Italia
Institución/País de afiliación:
Siksha O Anusandhan University/IN
/
University of Milan/IT