An in vitro evaluation of antimicrobial interaction between glycine and some penicillins using the decimal assay for additivity (daa) method
Journal of Pharmacetuical and Allied Sciences
; 3(1): 289-293, 2005.
Article
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| AIM
| ID: biblio-1264461
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CG1.1
ABSTRACT
The decimal assay for additivity (DAA) method was used to evaluate the in vitro interaction of glycine (Gly) with penicillin G (Pen G); cloxacillin (Clox) and ampicillin (Amp) against a clinical isolate of Staphylococcus aureus. In the interaction between Pen G/glycine with biological equivalent factor (BEF) 5 mg/62 mg; the decimal combination of 4 parts Pen G and 6 parts glycine showed amtagpmos; wjo;e ptjers sjpwed addotive effect In the interaction between Clox/glycine with BEF 1.26 og/62.5 mg ony 73 combination gave a synergistic effect. Others showed antagonism. In Amp/glycine combination with BEF; 1.74 og/62.5 mg; the decimal combinations of 46 gave additive effect; 91 gave synergistic effect while 73 combinaiton gave indifferent effect
Texto completo:
1
Base de datos:
AIM
Asunto principal:
Penicilinas
/
Investigación
/
Glicina
Idioma:
En
Revista:
Journal of Pharmacetuical and Allied Sciences
Año:
2005
Tipo del documento:
Article