Falla hepática aguda sobre crónica (ACLF), síndrome subdiagnosticado con alta mortalidad / Acute-on-chronic liver failure (ACLF), an underdiagnosed syndrome with high mortality
Rev. Hosp. Clin. Univ. Chile
; 32(1): 29-37, 2021. tab, graf
Article
en Es
| LILACS
| ID: biblio-1353347
Biblioteca responsable:
CL36.1
ABSTRACT
Acute on chronic liver failure is an increasingly recognized syndrome characterized by acute decompensation of chronic liver disease associated with organ failure and high short-term mortality. ACLF is frequent, affecting between 24 and 40% of patients admitted for complications of cirrhosis. Sepsis, active alcoholism, and relapse of chronic viral hepatitis are the most frequent precipitating factors. However, in up to 40%50% of the cases of ACLF have no identifiable trigger. The stage of severity of Acute on chronic liver failure is very important because it allows us to stratify patients according to their prognosis, evaluate therapeutic response, determine transplant urgency, deciding intensive care unit admission, and also have a basis on which to decide therapeutic futility. (AU)
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Insuficiencia Hepática Crónica Agudizada
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
Es
Revista:
Rev. Hosp. Clin. Univ. Chile
Asunto de la revista:
MEDICINA
Año:
2021
Tipo del documento:
Article
País de afiliación:
Chile
Pais de publicación:
Chile