Rectal application of argan oil improves healing of colorectal anastomosis in rats
Acta cir. bras
; 33(7): 565-576, July 2018. tab, graf
Artículo
en Inglés
| LILACS
| ID: biblio-949365
Biblioteca responsable:
BR1.1
ABSTRACT
Abstract Purpose:
To investigate the possible effects of argan oil on the healing of colorectal anastomoses.Methods:
I n Group 1 (sham), laparotomy was performed and the colon was mobilized. In the control (Group 2) and argan oil (Group 3) groups, colonic resection and anastomosis were applied. To the control and sham groups, 2 mL of 0.9% NaCl was administred rectally, and in the argan oil group, 2 mL/day argan oil was applied rectally for 7 days.Results:
The mean bursting pressures of the argan oil and sham groups were significantly higher than the values in the control group. A significant difference was determined between the tissue hydroxyproline and prolidase levels of control group and other groups. Histopathologically, argan oil showed significant beneficial effects on colonic wound healing. In the argan oil and sham groups, the tissue malondialdehyde and fluorescent oxidation product levels were found to be lower and total sulfhydryl levels were higher than the control group.Conclusions:
The rectally administered argan oil was observed to have significantly ameliorated wound healing parameters and exerted a significant antioxidant effect. This is the first study in the literature about the beneficial effects of argan oil on colorectal anastomoses.
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
LILACS
Asunto principal:
Recto
/
Cicatrización de Heridas
/
Aceites de Plantas
/
Colon
/
Antiinflamatorios
/
Antioxidantes
Tipo de estudio:
Estudio de evaluación
Límite:
Animales
Idioma:
Inglés
Revista:
Acta cir. bras
Asunto de la revista:
CIRURGIA GERAL
/
Procedimentos Cir£rgicos Operat¢rios
Año:
2018
Tipo del documento:
Artículo
País de afiliación:
Turquía
Institución/País de afiliación:
Ankara Education and Research Hospital/TR