Collagen I and III in women with diastasis recti
Clinics
; Clinics;73: e319, 2018. tab, graf
Article
en En
| LILACS
| ID: biblio-952786
Biblioteca responsable:
BR1.1
ABSTRACT
OBJECTIVES:
Interest in elucidating the etiology of hernias has encouraged countless studies of musculoaponeurotic structures in individuals with and without hernias. Studies of hernia patients have firmly demonstrated a correlation between hernias and collagen alterations in their fascia. Diastasis recti is an increased width of the abdominal midline that is exclusively composed of interlacing aponeurotic expansions of the anterolateral abdominal muscles. The condition is common among women undergoing abdominoplasty, and many factors, not only mechanical, play a role. The goal of this study is to evaluate and compare collagen type I and III levels in the midline fascia of women with and without diastasis recti to report their possible influence on this condition.METHODS:
This is a case-control study nested within a surgical cohort of 18 women with diastasis recti and 18 women without the condition (cases and controls, respectively). Fascia from the midline of the abdominal wall was collected and analyzed through immunohistochemistry using polyclonal antibodies to collagen type I and III.RESULTS:
Both type I and type III collagen were less abundant in women with diastasis recti than in those without the condition, and the difference was statistically significant (p<0.001).CONCLUSION:
Low collagen type I and type III levels in the midline of the abdominal wall may play a key role in the development of diastasis recti.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Síndrome del Abdomen en Ciruela Pasa
/
Colágeno Tipo I
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Colágeno Tipo III
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Pared Abdominal
Tipo de estudio:
Observational_studies
Límite:
Adult
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Female
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Humans
Idioma:
En
Revista:
Clinics
Asunto de la revista:
MEDICINA
Año:
2018
Tipo del documento:
Article
País de afiliación:
Brasil
Pais de publicación:
Brasil