Relación entre acumulación de rodamina 6G y resistencia a fluconazol en Saccharomyces cerevisiae S288c / Relationship between rhodamine 6G accumulation and fluconazole resistance in Saccharomyces cerevisiae S288c
Rev. argent. microbiol
; 32(3): 157-160, jul.-sept. 2000.
Artículo
en Español
| BINACIS
| ID: bin-6733
Biblioteca responsable:
BR1.1
ABSTRACT
Severe mycotic infections are a source of concern in immunocompromised patients or in those who receive chemotherapy for hematological malignant diseases. One of the causes is referred to the appearance of antimycotic resistant microorganisms. Fluconazole is one of the antimycotic used for invasive mycoses treatment. Therefore it is necessary to evaluate the factors that originate this resistance. In the present report the yeast Saccharomyces cerevisiae S288c was used as a model system. In resistant strains the accumulation of the lipophilic cation Rhodamine 6G, L-leucine uptake and growth inhibition by crystal violet dye were determined. The results presented herein demonstrate the correlation between the membrane potential and the resistance to fluconazole presented by S. cerevisiae strain S288c.(AU)
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Colección:
Bases de datos nacionales
/
Argentina
Base de datos:
BINACIS
Asunto principal:
Rodaminas
/
Saccharomyces cerevisiae
/
Farmacorresistencia Microbiana
/
Fluconazol
/
Potenciales de la Membrana
/
Antifúngicos
Tipo de estudio:
Estudio pronóstico
Idioma:
Español
Revista:
Rev. argent. microbiol
Año:
2000
Tipo del documento:
Artículo
Institución/País de afiliación:
Universidad de Buenos Aires/Argentina