Unilateral submandibular gland aplasia with ipsilateral sublingualgland hypertrophy presenting as a neck mass

ABSTRACT

The congenital absence of the major salivary glands is a very infrequent disorder, in which several glands are usuallyinvolved at the same time. Sometimes this disorder can be associated with other developmental anomalies.The unilateral aplasia of the submandibular gland is an extremely rare finding with only 14 cases reported in theliterature. Clinically, this kind of patients may complain of dryness of the mouth, difficulties in chewing and swallowing,severe periodontal disease or multiple caries, but usually they follow an asymptomatic course. Salivarygland aplasia can be diagnosed with a large variety of imaging techniques, which include computer tomography(CT), magnetic resonance imaging (MR), ultrasonography (US), sialography, or scintigraphy. In this paper wereport a case of a patient referred to our department with a long term and progressive growing neck mass, who hasan unilateral submandibular gland aplasia associated to an ipsilateral hypertrophy of the sublingual gland (AU)