Correlación entre clearence de creatinina de 4 horas y la prueba de Cr-EDTA / Correlation between 4 hours creatinine clearence and Cr-EDTA test
Rev. méd. Chile
; 123(5): 600-4, mayo 1995. tab, ilus
Article
en Es
| LILACS
| ID: lil-152862
Biblioteca responsable:
CL1.1
RESUMEN
Creatinine clearence as a measure of glomerular filtration rate has several sources of error such as tubular creatinine secretion or faulty urine collections. On the other hand 51Cr-EDTA test is reliable and accurate, except in patients with edema, in whom the radioisotope equilibrium is retarded after injection. Aim:
to validate a 4 hours creatinine clearence correlating it with 51Cr-EDTA test.Methods:
In 59 non insulin dependent diabetic patients without diabetic nephropathy, glomerular filtration rate was measured using one 50 µCi injection of 51Cr-EDTA and collecting blood samples for radioactivity measurement at 10, 30, 120 and 240 min. Simultaneously, creatinine clearence was measured using a 4 hours urine collection.Results:
The general correlation coefficient between both methods was 0,85 (p<0,001). For glomerular filtration rates below 95 ml/min, the correlation coefficient was 0,8(p<0,001), for values between 95 and 127 ml/min, the correlation was 0,51(p<0,001) and for values over 127 ml/min the correlation was 0,8(p<0,001). The regression equation obtained was y=1,2x+13 where y was the glomerular filtration rate measured with 51Cr-EDTA and x the same value measured with creatinine clearence.Conclusions:
The four hours creatinine clearence is a reliable method to estimate glomerular filtration rate
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Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Ácido Edético
/
Creatinina
/
Diabetes Mellitus Tipo 2
/
Tasa de Filtración Glomerular
Límite:
Humans
Idioma:
Es
Revista:
Rev. méd. Chile
Asunto de la revista:
MEDICINA
Año:
1995
Tipo del documento:
Article
/
Project document
Pais de publicación:
Chile