Muscle pathology in juvenile dermatomyositis
São Paulo med. j
; São Paulo med. j;115(5): 1555-9, set.-out. 1997. ilus, tab
Article
en En
| LILACS
| ID: lil-209340
Biblioteca responsable:
BR1.1
RESUMO
To study muscle biopsies, using histochemistry, on ten children with infantile dermatomyositis. Design:
Series of ten patients (of whom eight patients had received treatment and two had not) were submitted to muscle biopsy in order to diagnose possible inflammatory myopathy or to detect recurrences. Place of development of the study Public Health Service of Sao Paulo State.Participants:
children with clinical features of inflammatory myopathy. Intervention biopsies were performed on the vastus lateralis using local anesthetic. Histochemistry was performed according to standardized methods.Results:
Architectural changes of the muscle fibers, necrosis of variable intensity and accentuated evidence of regeneration were observed in patients who had not received treatment (2 cases) and in one case where muscular weakness persisted in spite of corticosteroid therapy. Necrosis and regeneration were minimal or absent in cases treated for one year or more (4 cases). In 3 cases with clinical and laboratorial recurrences, muscle necrosis and architectural changes were detected.Conclusions:
It was concluded that muscle biopsy could aid in diagnosing infantile dermatomyositis as well as in detecting recurrences even in cases without clinical activity of the disease.
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Dermatomiositis
/
Músculos
Tipo de estudio:
Diagnostic_studies
Límite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
Idioma:
En
Revista:
São Paulo med. j
Asunto de la revista:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
MEDICINA
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Año:
1997
Tipo del documento:
Article
Pais de publicación:
Brasil