Hiperinsulinismo neonatal persistente: análisis del diagnóstico diferencial a propósito de dos casos clínicos / Persistent neonatal hyperinsulinism: report of two cases
Rev. méd. Chile
; 132(8): 995-1000, ago. 2004. ilus, tab
Article
en Es
| LILACS
| ID: lil-384197
Biblioteca responsable:
CL12.1
ABSTRACT
Persistent neonatal hyperinsulinism is the most common cause of refractory hypoglycemia during the first year of life. Inadequate insulin secretion is associated to mutations of four different genes, that can be diagnosed to orient patient management. We report two patients a female newborn that presented a hypoglycemia of 16 mg/dl two hours after birth, was subjected to a subtotal pancreatectomy that did not correct hypoglycemia, requiring a total pancreatectomy. Pathological study of the pancreas showed a focal adenomatous hyperplasia. At the present time, she is three years of age and maintains euglycemia with fractionated feeding. A male newborn that had seizures at 28 hours of life and a hypoglycemia of 15 mg/dl was detected. He was also subjected to a subtotal pancreatectomy, that did not correct hypoglycemia and had to be extended to a total pancreatectomy. At the present time, he is 3 years and 11 months of age and has a normal psychomotor development (Rev Méd Chile 2004; 132 995-1000).
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Páncreas
/
Pancreatectomía
/
Hiperinsulinismo Congénito
Tipo de estudio:
Diagnostic_studies
Límite:
Female
/
Humans
/
Male
/
Newborn
Idioma:
Es
Revista:
Rev. méd. Chile
Asunto de la revista:
MEDICINA
Año:
2004
Tipo del documento:
Article
País de afiliación:
Chile
Pais de publicación:
Chile