Initial Results and Clinical Application of Non Dedicated 18-FDG/PET in Head and Neck Oncology
Appl. cancer res
; 25(1): 25-31, Jan.-Mar. 2005.
Article
en En
| LILACS, Inca
| ID: lil-442294
Biblioteca responsable:
BR30.1
ABSTRACT
Imaging procedures are important methods for properstage and treatment planning. Especially in previouslytreated patients, although not perfectly accurate. PETscan is a functional and imaging technique that has beenused to diagnose and stage recurrent cancer fromdifferent sites. The combination of computedtomography coupled with FDG-PET (18-FDG-PET/CT)reaches high quality anatomical and functional images.OBJECTIVE:
To describe the initial results of FDG-PET/CT performed at a single institution. MATERIAL ANDMETHODS:
This technique was used in 63 patients withhead and neck tumors. The purpose of the exam was a)to rule out recurrent disease - 55 patients; b) to search forhidden primary tumor - 2 patients; and c) postoperativefollow-up of residual disease - 6 patients. Computedtomography (CT) was performed in 56 cases (88.9%).Pathological confirmation was obtained in 24 cases(38.1%), all the remaining cases were considered negativebased on clinical follow-up information with no evidenceof recurrent disease 12 months after the PET/CT exam.RESULTS:
Overall results for the accuracy of FDG-PETwere 93.9% of sensitivity, 64.2% of specificity, 75.6% ofpositive predictive value and 90.0% of negativepredictive value. FDG-PET was able to find 1 out of 2undetected primary tumors (base of the tongue). Thebest results were obtained regarding the detection oflocal and distant recurrences of larynx, thyroid and oralcavity cancers.CONCLUSION:
The FDG-PET/CT fusionimage makes anatomical localization easier and theaccuracy for detection of recurrent disease was found tobe higher than CT alone.
Texto completo:
1
Colección:
01-internacional
Base de datos:
LILACS
/
Inca
Asunto principal:
Tomografía de Emisión de Positrones
/
Neoplasias de Cabeza y Cuello
Límite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
Appl. cancer res
Asunto de la revista:
NEOPLASIAS
Año:
2005
Tipo del documento:
Article
País de afiliación:
Brasil
Pais de publicación:
Brasil