Pattern of acquisition of rotavirus antibody in children followed up from birth to the age of three years
Rev. Soc. Bras. Med. Trop
; Rev. Soc. Bras. Med. Trop;22(1): 25-9, jan.-mar. 1989. ilus
Article
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| LILACS
| ID: lil-87195
Biblioteca responsable:
BR1.1
ABSTRACT
Nine hundred and forty-eight serum samples from 83 children living in Belem, Brazil, collected within their first three years oflife, were tested for the presence of groupspecific rotavirus-antibody by an enzyme-linked immunosorbent assay (Elisa) blocking-test. Passively transferred maternal antibody lasted about two and half months; subsenquentely, low levels of rotavirus antibody started to appear at seven months, reaching a peak at eleven months of age. From one year onwards positivity gradually increased, reaching highest values at 34 months of life. Individual responses were examined in sera from 61 children who were followed up since birth to three years of age 38 (62,3%) of them developed a long-term immunity following first infection; eleven (18.0%) children developed a short-term immunity after first infection by rotavirus; seven (11.5%) had no antibody response within their first three years of life; and 5 (8.2%) showed positive antibody response from birth to three years old
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Colección:
01-internacional
Base de datos:
LILACS
Asunto principal:
Rotavirus
/
Anticuerpos Antivirales
Tipo de estudio:
Observational_studies
/
Prognostic_studies
Límite:
Humans
/
Newborn
Idioma:
En
Revista:
Rev. Soc. Bras. Med. Trop
Asunto de la revista:
MEDICINA TROPICAL
Año:
1989
Tipo del documento:
Article
Pais de publicación:
Brasil