Construction of centrosomes and spindle poles by molecular motor-driven assembly of protein particles.
Traffic
; 1(12): 927-34, 2000 Dec.
Article
en En
| MEDLINE
| ID: mdl-11208082
ABSTRACT
Centrosomes and other microtubule organizing centers are the largest non-membranous organelles in most cells. This morphologically diverse class of organelles shares a common ability to nucleate and organize microtubules in interphase and participates in the formation of mitotic spindles during cell division. This review summarizes recent evidence suggesting that assembly of centrosomes and mitotic spindle poles require transport of large protein particles along microtubules by the molecular motor cytoplasmic dynein.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Dineínas
/
Centrosoma
/
Proteínas de Ciclo Celular
/
Proteínas Motoras Moleculares
/
Huso Acromático
Límite:
Animals
Idioma:
En
Revista:
Traffic
Asunto de la revista:
FISIOLOGIA
Año:
2000
Tipo del documento:
Article
País de afiliación:
Estados Unidos