Iron(III) reducing and antiradical activities of three Sideritis from Turkey.
Pharm Biol
; 49(8): 800-4, 2011 Aug.
Article
en En
| MEDLINE
| ID: mdl-21500963
ABSTRACT
CONTEXT Sideritis species (Lamiaceae) are widely used as herbal tea and have been used in folk medicine for their anti-inflammatory, anti-rheumatic, digestive, and antimicrobial activities in Turkey. Sideritis dichotoma Huter., Sideritis erythrantha Boiss. var. cedrotorum, and Sideritis vuralii H. Duman et Baser are available as commercial products in Turkey. OBJECTIVE:
The antiradical activities of the various solvent extracts of Sideritis species are investigated here for the first time. MATERIALS ANDMETHODS:
Plant samples were sequentially extracted with n-hexane, dichloromethane, methanol, and aqueous methanol (50%, v/v) in Soxhlet apparatus. The extracts of Camellia sinensis (L.) Kuntze (Theaceae) were also prepared for use as a positive control. Total phenolics, iron(III) reductive effects, and 1,1-diphenyl-2-picrylhydrazyl (DPPHâ¢) radical scavenging activities of the all extracts were measured colorimetrically.RESULTS:
The aqueous MeOH and MeOH extracts contained the highest amount of total phenols, whereas the n-hexane extract contained the lowest amounts. The polar extracts of C. sinensis showed higher antiradical activity and also iron(III) reductive effects than the Sideritis species; however, the non-polar extracts of Sideritis species were found to be more active than those from C. sinensis in the iron(III) reductive assay and in the DPPH(â¢) assay as well. But none of the extracts was found to be as active as with positive controls, viz., ascorbic acid, butylated hydroxyanisole (BHA), and Trolox. DISCUSSION ANDCONCLUSION:
These results can be shown to have antioxidant activities of these Sideritis species and support the ethnopharmacological use of these Sideritis plants.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Extractos Vegetales
/
Depuradores de Radicales Libres
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Sideritis
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Hierro
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Antioxidantes
País/Región como asunto:
Asia
Idioma:
En
Revista:
Pharm Biol
Año:
2011
Tipo del documento:
Article
País de afiliación:
Finlandia