ELA-DRA polymorphisms are not associated with Equine Arteritis Virus infection in horses from Argentina.
Res Vet Sci
; 93(3): 1271-3, 2012 Dec.
Article
en En
| MEDLINE
| ID: mdl-22534582
Polymorphisms at Major Histocompatibility Complex (MHC) genes have been associated with resistance/susceptibility to infectious diseases in domestic animals. The aim of this investigation was to evaluate whether polymorphisms of the DRA gene the Equine Lymphocyte Antigen is associated with susceptibility to Equine Arteritis Virus (EAV) infection in horses in Argentina. The equine DRA gene was screened for polymorphisms using Pyrosequencing® Technology which allowed the detection of three ELA-DRA exon 2 alleles. Neither allele frequencies nor genotypic differentiation exhibited any statistically significant (P-values=0.788 and 0.745) differences between the EAV-infected and no-infected horses. Fisher's exact test and OR calculations did not show any significant association. As a consequence, no association could be established between the serological condition and ELA-DRA.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Infecciones por Arterivirus
/
Equartevirus
/
Enfermedades de los Caballos
/
Complejo Mayor de Histocompatibilidad
Tipo de estudio:
Risk_factors_studies
Límite:
Animals
País/Región como asunto:
America do sul
/
Argentina
Idioma:
En
Revista:
Res Vet Sci
Año:
2012
Tipo del documento:
Article
País de afiliación:
Argentina
Pais de publicación:
Reino Unido