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Evaluation of the antioxidant capacity of synthesized coumarins.
Vianna, Damiana R; Bubols, Guilherme; Meirelles, Gabriela; Silva, Bárbara V; Da Rocha, Alessandra; Lanznaster, Maurício; Monserrat, José Maria; Garcia, Solange Cristina; Von Poser, Gilsane; Eifler-Lima, Vera Lucia.
Afiliación
  • Vianna DR; Post-Graduate Program in Pharmaceutical Sciences, Federal University of Rio Grande do Sul, Av. Ipiranga, 2752, 90610-000, Porto Alegre, RS, Brazil.
  • Bubols G; Post-Graduate Program in Pharmaceutical Sciences, Federal University of Rio Grande do Sul, Av. Ipiranga, 2752, 90610-000, Porto Alegre, RS, Brazil.
  • Meirelles G; Post-Graduate Program in Pharmaceutical Sciences, Federal University of Rio Grande do Sul, Av. Ipiranga, 2752, 90610-000, Porto Alegre, RS, Brazil.
  • Silva BV; Institute of Chemistry, Federal University of Rio de Janeiro, UFRJ, Bloco A, Cidade Universitária, 21941-909, Rio de Janeiro, RJ, Brazil.
  • Da Rocha A; Post-Graduate Program in Physiological Sciences, Comparative Animal Physiology, Institute of Biological Sciences, Federal University of Rio Grande, FURG, Av Itália km 8 s/n, 96201-900, Rio Grande, RS, Brazil.
  • Lanznaster M; Institute of Chemistry, Universidade Federal Fluminense, UFF, Outeiro de São João Batista, s/n, Campus do Valonguinho Centro, 24020-150, Niterói, RJ, Brazil.
  • Monserrat JM; Post-Graduate Program in Physiological Sciences, Comparative Animal Physiology, Institute of Biological Sciences, Federal University of Rio Grande, FURG, Av Itália km 8 s/n, 96201-900, Rio Grande, RS, Brazil.
  • Garcia SC; Post-Graduate Program in Pharmaceutical Sciences, Federal University of Rio Grande do Sul, Av. Ipiranga, 2752, 90610-000, Porto Alegre, RS, Brazil.
  • Von Poser G; Post-Graduate Program in Pharmaceutical Sciences, Federal University of Rio Grande do Sul, Av. Ipiranga, 2752, 90610-000, Porto Alegre, RS, Brazil.
  • Eifler-Lima VL; Post-Graduate Program in Pharmaceutical Sciences, Federal University of Rio Grande do Sul, Av. Ipiranga, 2752, 90610-000, Porto Alegre, RS, Brazil.
Int J Mol Sci ; 13(6): 7260-7270, 2012.
Article en En | MEDLINE | ID: mdl-22837692
Coumarins are secondary metabolites that are widely distributed within the plant kingdom, some of which have been extensively studied for their antioxidant properties. The antioxidant activity of coumarins assayed in the present study was measured by different methods, namely the 1,1-diphenyl-2-picryl-hydrazyl (DPPH(•)) method, cyclic voltammetry and the antioxidant capacity against peroxyl radicals (ACAP) method. The 7,8-dihydroxy-4-methylcoumarin (LaSOM 78), 5-carboxy-7,8-dihydroxy-4-methylcoumarin (LaSOM 79), and 6,7-dihydroxycoumarin (Esculetin) compounds proved to be the most active, showing the highest capacity to deplete the DPPH radicals, the highest antioxidant capacity against peroxyl radicals, and the lowest values of potential oxidation.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Peróxidos / Umbeliferonas / Antioxidantes Tipo de estudio: Evaluation_studies Idioma: En Revista: Int J Mol Sci Año: 2012 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Suiza
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Peróxidos / Umbeliferonas / Antioxidantes Tipo de estudio: Evaluation_studies Idioma: En Revista: Int J Mol Sci Año: 2012 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Suiza