Characterization of the CD40L/Oncostatin M/Oncostatin M receptor axis as an antiviral and immunostimulatory system disrupted in chronic HCV infection.

Larrea, Esther; Echeverria, Itziar; Riezu-Boj, Jose-I; Aldabe, Rafael; Guembe, Laura; Sola, Iosu; Civeira, María Pilar; Sarobe, Pablo; Prieto, Jesus

Larrea, Esther; Echeverria, Itziar; Riezu-Boj, Jose-I; Aldabe, Rafael; Guembe, Laura; Sola, Iosu; Civeira, María Pilar; Sarobe, Pablo; Prieto, Jesus.

Afiliación

Larrea E; Division of Hepatology and Gene Therapy, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain. Electronic address: elarrea@unav.es.
Echeverria I; Division of Hepatology and Gene Therapy, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.
Riezu-Boj JI; Division of Hepatology and Gene Therapy, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.
Aldabe R; Division of Hepatology and Gene Therapy, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.
Guembe L; Department of Morphology, CIMA, University of Navarra, Pamplona, Spain.
Sola I; University Clinic of Navarra, University of Navarra, Pamplona, Spain.
Civeira MP; University Clinic of Navarra, University of Navarra, Pamplona, Spain.
Sarobe P; Division of Hepatology and Gene Therapy, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain.
Prieto J; Division of Hepatology and Gene Therapy, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain; University Clinic of Navarra, University of Navarra, Pamplona, Spain; CIBERehd, University of Navarra, Pamplona, Spain. Electronic address: jprieto@unav.es.

J Hepatol ; 60(3): 482-9, 2014 Mar.

Article en En | MEDLINE | ID: mdl-24418171

Asunto(s)

Ligando de CD40/fisiología; Hepatitis C Crónica/inmunología; Subunidad beta del Receptor de Oncostatina M/fisiología; Oncostatina M/fisiología; Células Presentadoras de Antígenos/inmunología; Linfocitos T CD4-Positivos/inmunología; Humanos; Monocitos/inmunología; Factor de Transcripción STAT3/fisiología

Palabras clave

APC; CD40 ligand; CD40L; CHC; CLC; DCs; HCV; IFN; LIFR; LPS; MoDCs; OSM; OSM receptor beta subunit; OSMRß; PBMC; PGN; Poly I:C; RT-PCR; SVR; TLR; antigen presenting cells; cardiotrophin-like-cytokine; chronic hepatitis C; dendritic cells; hepatitis C virus; interferon; leukemia inhibitory factor receptor; lipopolysaccharide; monocyte-derived-DCs; oncostatin M; peptidoglycan; peripheral mononuclear cells; polyinosinic:polycytidylic acid; qPCR; quantitative real time PCR; reverse transcription polymerase chain reaction; sustained virological response; toll-like receptors

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hepatitis C Crónica / Ligando de CD40 / Oncostatina M / Subunidad beta del Receptor de Oncostatina M Límite: Humans Idioma: En Revista: J Hepatol Asunto de la revista: GASTROENTEROLOGIA Año: 2014 Tipo del documento: Article

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