Acute-phase response to scalding: changes in serum properties and acute-phase protein concentrations.
Circ Shock
; 28(3): 293-307, 1989 Jul.
Article
en En
| MEDLINE
| ID: mdl-2475272
ABSTRACT
The time course of changes in the concentrations of individual acute-phase proteins (APRs) in the plasma was examined in the model of rats exposed to a single (sublethal) and repeated (fatal) scalding. These data were interrelated with the rate of survival, plasma volume, corticosterone level, and immunosuppressive potency of the serum. The infliction of a sublethal scalding composing 20% body surface area resulted in an initial 50% reduction of the plasma volume and a severalfold increase of the corticosterone level and immunosuppressive activity of the serum. A subsequent normalisation of these deviations proceeded in parallel with an increased rate of APR synthesis. An early infliction of a second scald was fatal. It led to a 60% reduction of the plasma volume, a lack of plasma APRs, and an additional enhancement of the immunosuppressive activity of serum.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Quemaduras
/
Proteínas de Fase Aguda
Límite:
Animals
Idioma:
En
Revista:
Circ Shock
Año:
1989
Tipo del documento:
Article
País de afiliación:
Yugoslavia