Targeting the actin cytoskeleton: selective antitumor action via trapping PKCÉ.

Foerster, F; Braig, S; Moser, C; Kubisch, R; Busse, J; Wagner, E; Schmoeckel, E; Mayr, D; Schmitt, S; Huettel, S; Zischka, H; Mueller, R; Vollmar, A M

Targeting the actin cytoskeleton: selective antitumor action via trapping PKCÉ.

Foerster, F; Braig, S; Moser, C; Kubisch, R; Busse, J; Wagner, E; Schmoeckel, E; Mayr, D; Schmitt, S; Huettel, S; Zischka, H; Mueller, R; Vollmar, A M.

Afiliación

Foerster F; Department of Pharmacy, Pharmaceutical Biology, University of Munich, Munich, Germany.
Braig S; Department of Pharmacy, Pharmaceutical Biology, University of Munich, Munich, Germany.
Moser C; Department of Pharmacy, Pharmaceutical Biology, University of Munich, Munich, Germany.
Kubisch R; Department of Pharmacy, Pharmaceutical Biology, University of Munich, Munich, Germany.
Busse J; Department of Pharmacy, Pharmaceutical Biotechnology, University of Munich, Munich, Germany.
Wagner E; Department of Pharmacy, Pharmaceutical Biotechnology, University of Munich, Munich, Germany.
Schmoeckel E; Institute of Pathology, University of Munich, Munich, Germany.
Mayr D; Institute of Pathology, University of Munich, Munich, Germany.
Schmitt S; Institute for Molecular Toxicology and Pharmacology, Helmholtz Centre Munich, German Research Center for Environmental Health, Neuherberg, Germany.
Huettel S; Institute of Pathology, University of Munich, Munich, Germany.
Zischka H; Institute for Molecular Toxicology and Pharmacology, Helmholtz Centre Munich, German Research Center for Environmental Health, Neuherberg, Germany.
Mueller R; Helmholtz Institute for Pharmaceutical Research Saarland, Helmholtz Centre for Infection Research and Department of Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany.
Vollmar AM; Department of Pharmacy, Pharmaceutical Biology, University of Munich, Munich, Germany.

Cell Death Dis ; 5: e1398, 2014 Aug 28.

Article en En | MEDLINE | ID: mdl-25165884

Asunto(s)

Citoesqueleto de Actina/metabolismo; Actinas/metabolismo; Proteína Quinasa C/metabolismo; Citoesqueleto de Actina/efectos de los fármacos; Actinas/genética; Animales; Antineoplásicos/uso terapéutico; Antineoplásicos/toxicidad; Apoptosis/efectos de los fármacos; Sitios de Unión; Neoplasias de la Mama/tratamiento farmacológico; Neoplasias de la Mama/patología; Línea Celular Tumoral; Proliferación Celular/efectos de los fármacos; Citocromos c/metabolismo; Depsipéptidos/uso terapéutico; Depsipéptidos/toxicidad; Femenino; Recuperación de Fluorescencia tras Fotoblanqueo; Hexoquinasa/metabolismo; Humanos; Células MCF-7; Potencial de la Membrana Mitocondrial/efectos de los fármacos; Ratones; Ratones SCID; Mitocondrias/metabolismo; Fosfatidilserinas/farmacología; Transducción de Señal; Trasplante Heterólogo; Canales Aniónicos Dependientes del Voltaje/metabolismo; Proteína Letal Asociada a bcl/metabolismo

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Citoesqueleto de Actina / Proteína Quinasa C / Actinas Límite: Animals / Female / Humans Idioma: En Revista: Cell Death Dis Año: 2014 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Reino Unido

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