Cytotoxic and genotoxic effects of ethanolic extract of Euphorbia hyssopifolia L. on HepG2 cells.

Araújo, Silvany de Sousa; Fernandes, Thaís Cristina Casimiro; Cardona, Yaliana Tafurt; Almeida, Pedro Marcos de; Marin-Morales, Maria Aparecida; Dos Santos, Andrea Vidal; Randau, Karina Perrelli; Benko-Iseppon, Ana Maria; Brasileiro-Vidal, Ana Christina

Araújo, Silvany de Sousa; Fernandes, Thaís Cristina Casimiro; Cardona, Yaliana Tafurt; Almeida, Pedro Marcos de; Marin-Morales, Maria Aparecida; Dos Santos, Andrea Vidal; Randau, Karina Perrelli; Benko-Iseppon, Ana Maria; Brasileiro-Vidal, Ana Christina.

Afiliación

Araújo Sde S; Federal University of Pernambuco, Centre of Biological Sciences, Genetics Department, 50670-420 Recife, PE, Brazil.
Fernandes TC; São Paulo State University "Júlio de Mesquita Filho", Institut of Biosciences of Rio Claro, Department of Biology, 13506-900 Rio Claro, SP, Brazil.
Cardona YT; São Paulo State University "Júlio de Mesquita Filho", Institut of Biosciences of Rio Claro, Department of Biology, 13506-900 Rio Claro, SP, Brazil.
Almeida PM; Federal University of Pernambuco, Centre of Biological Sciences, Genetics Department, 50670-420 Recife, PE, Brazil.
Marin-Morales MA; São Paulo State University "Júlio de Mesquita Filho", Institut of Biosciences of Rio Claro, Department of Biology, 13506-900 Rio Claro, SP, Brazil.
Dos Santos AV; Federal University of Pernambuco, Centre of Health Sciences, Pharmaceutical Sciences Department, 50670-420 Recife, PE, Brazil.
Randau KP; Federal University of Pernambuco, Centre of Health Sciences, Pharmaceutical Sciences Department, 50670-420 Recife, PE, Brazil.
Benko-Iseppon AM; Federal University of Pernambuco, Centre of Biological Sciences, Genetics Department, 50670-420 Recife, PE, Brazil.
Brasileiro-Vidal AC; Federal University of Pernambuco, Centre of Biological Sciences, Genetics Department, 50670-420 Recife, PE, Brazil. Electronic address: brasileirovidal.ac@gmail.com.

J Ethnopharmacol ; 170: 16-9, 2015 Jul 21.

Article en En | MEDLINE | ID: mdl-25937254

Asunto(s)

Euphorbia/química; Mutágenos/toxicidad; Extractos Vegetales/toxicidad; Muerte Celular/efectos de los fármacos; Ensayo Cometa; Relación Dosis-Respuesta a Droga; Etanol/química; Euphorbia/metabolismo; Células Hep G2; Humanos; Pruebas de Micronúcleos; Mutágenos/aislamiento & purificación; Extractos Vegetales/administración & dosificación; Metabolismo Secundario

Palabras clave

Antimicrobial; Botany; Cell death; Comet assay; Cytochalasin B (PubChem CID: 5368686); Cytotoxicity; Dimethyl Sulfoxide (PubChem CID: 679); Ethanol (PubChem CID: 702); Ethanolic extract; Euphorbiaceae; Methyl methanesulfonate (PubChem CID: 4156); Micronucleus; Mutagenesis; Octoxynol (PubChem CID: 5590); Sodium pyruvate (PubChem CID: 23662274); Thiazolyl blue (PubChem CID: 64965); Traditional medicine Africa; Traditional medicine meso- and Southern America

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Extractos Vegetales / Euphorbia / Mutágenos Límite: Humans Idioma: En Revista: J Ethnopharmacol Año: 2015 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Irlanda

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