Autofagia; Proteínas de Unión a Calmodulina/deficiencia; MicroARNs/metabolismo; Proteínas Supresoras de Tumor/metabolismo; Animales; Autofagia/genética; Secuencia de Bases; Proteínas de Unión a Calmodulina/metabolismo; Regulación hacia Abajo/genética; Embrión de Mamíferos/citología; Fibroblastos/metabolismo; Ratones; Ratones Noqueados; Datos de Secuencia Molecular; Células 3T3 NIH; Proteína EWS de Unión a ARN; Proteínas de Unión al ARN; Transcripción Genética

AGO2, argonaute; ATG12, autophagy-related 12; ATG14, autophagy-related 14; ATG5, autophagy-related 5; Ant-Mir125a; Ant-Mir351; BECN1, Beclin 1; CNT-Ant, control antagomir; CQ, chloroquine; DGCR8, DiGeorge syndrome critical region gene 8; EWS, Ewing's Sarcoma; EWSR1; EWSR1, EWS RNA-binding protein 1/Ewing Sarcoma Break Point Region 1; Ewsr1+/+; Ewsr1 homozygous knockout; Ewsr1 wild type; ewsr1−/−; LAMP, lysosomal-associated membrane protein; MAP1LC3/LC3; MEF, mouse embryonic fibroblast; Mir125a; Mir125a-specific antagomir; Mir351; Mir351-specific antagomir; Pep.A, pepstatin A; RISC, catalytic component 2; RNA-seq, whole transcriptome sequencing; SQSTM1, sequestosome 1; UVRAG; UVRAG, UV radiation-resistance associated; autophagy; miRNA, microRNA; microtubule-associated protein 1 light chain 3; pri-miRNA, primary transcript miRNA; siRNA, small interfering RNA