Substrate specificity of mitochondrial intermediate peptidase analysed by a support-bound peptide library.

Marcondes, M F M; Alves, F M; Assis, D M; Hirata, I Y; Juliano, L; Oliveira, V; Juliano, M A

Marcondes, M F M; Alves, F M; Assis, D M; Hirata, I Y; Juliano, L; Oliveira, V; Juliano, M A.

Afiliación

Marcondes MF; Department of Biophysics, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Pedro de Toledo, 669 - 7° andar, São Paulo, Brazil.
Alves FM; Department of Biophysics, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Pedro de Toledo, 669 - 7° andar, São Paulo, Brazil.
Assis DM; Department of Biophysics, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Pedro de Toledo, 669 - 7° andar, São Paulo, Brazil.
Hirata IY; Department of Biophysics, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Pedro de Toledo, 669 - 7° andar, São Paulo, Brazil.
Juliano L; Department of Biophysics, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Pedro de Toledo, 669 - 7° andar, São Paulo, Brazil.
Oliveira V; Department of Biophysics, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Pedro de Toledo, 669 - 7° andar, São Paulo, Brazil.
Juliano MA; Department of Biophysics, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Pedro de Toledo, 669 - 7° andar, São Paulo, Brazil.

FEBS Open Bio ; 5: 429-36, 2015.

Article en En | MEDLINE | ID: mdl-26082885

Palabras clave

Abz, ortho-aminobenzoic acid; DCM, dichloromethane; DIPEA, N,N-diisopropylethylamine; DMF, dimethylformamide; EDDnp, N-(2,4-dinitrophenyl)-ethylenediamine; FRET libraries; FRET, fluorescence resonance energy transfer; HOBt, hydroxybenzotriazole; Mitochondria; NMM, N-methylmorpholine; Octapeptidyl amino peptidase 1; Peptidase; Substrate specificity; TBTU, O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; hMIP, human mitochondrial intermediate peptidase; oct1

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: FEBS Open Bio Año: 2015 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Reino Unido

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