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Synthesis of Biologically Active Piperidine Metabolites of Clopidogrel: Determination of Structure and Analyte Development.
Shaw, Scott A; Balasubramanian, Balu; Bonacorsi, Samuel; Cortes, Janet Caceres; Cao, Kevin; Chen, Bang-Chi; Dai, Jun; Decicco, Carl; Goswami, Animesh; Guo, Zhiwei; Hanson, Ronald; Humphreys, W Griffith; Lam, Patrick Y S; Li, Wenying; Mathur, Arvind; Maxwell, Brad D; Michaudel, Quentin; Peng, Li; Pudzianowski, Andrew; Qiu, Feng; Su, Shun; Sun, Dawn; Tymiak, Adrienne A; Vokits, Benjamin P; Wang, Bei; Wexler, Ruth; Wu, Dauh-Rurng; Zhang, Yingru; Zhao, Rulin; Baran, Phil S.
Afiliación
  • Shaw SA; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Balasubramanian B; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Bonacorsi S; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Cortes JC; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Cao K; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Chen BC; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Dai J; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Decicco C; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Goswami A; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Guo Z; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Hanson R; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Humphreys WG; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Lam PY; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Li W; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Mathur A; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Maxwell BD; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Michaudel Q; ‡Department of Chemistry, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, United States.
  • Peng L; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Pudzianowski A; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Qiu F; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Su S; ‡Department of Chemistry, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, United States.
  • Sun D; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Tymiak AA; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Vokits BP; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Wang B; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Wexler R; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Wu DR; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Zhang Y; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Zhao R; †Research and Development, Bristol-Myers Squibb Company, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States.
  • Baran PS; ‡Department of Chemistry, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, United States.
J Org Chem ; 80(14): 7019-32, 2015 Jul 17.
Article en En | MEDLINE | ID: mdl-26151079

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piperidinas / Ticlopidina / Microsomas Hepáticos / Inhibidores de Agregación Plaquetaria / Profármacos Límite: Humans Idioma: En Revista: J Org Chem Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piperidinas / Ticlopidina / Microsomas Hepáticos / Inhibidores de Agregación Plaquetaria / Profármacos Límite: Humans Idioma: En Revista: J Org Chem Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos