W346 inhibits cell growth, invasion, induces cycle arrest and potentiates apoptosis in human gastric cancer cells in vitro through the NF-&#954;B signaling pathway.

Xia, Yiqun; Weng, Bixia; Wang, Zhankun; Kang, Yanting; Shi, Lingyi; Huang, Guanqun; Ying, Shilong; Du, Xiaojing; Chen, Qiuxiang; Jin, Rong; Wu, Jianzhang; Liang, Guang

W346 inhibits cell growth, invasion, induces cycle arrest and potentiates apoptosis in human gastric cancer cells in vitro through the NF-κB signaling pathway.

Xia, Yiqun; Weng, Bixia; Wang, Zhankun; Kang, Yanting; Shi, Lingyi; Huang, Guanqun; Ying, Shilong; Du, Xiaojing; Chen, Qiuxiang; Jin, Rong; Wu, Jianzhang; Liang, Guang.

Afiliación

Xia Y; Department of Digestive Diseases, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
Weng B; Chemical Biology Research Center, College of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Wang Z; Chemical Biology Research Center, College of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Kang Y; Pharmacy Department, Tonglu First People's Hospital, Hangzhou, Zhejiang, 311500, China.
Shi L; Institute of Sports Science, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Huang G; Department of Digestive Diseases, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
Ying S; Chemical Biology Research Center, College of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Du X; Chemical Biology Research Center, College of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Chen Q; Department of General Surgery, The fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510700, China.
Jin R; Chemical Biology Research Center, College of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.
Wu J; Department of Digestive Diseases, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China.
Liang G; Chemical Biology Research Center, College of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China.

Tumour Biol ; 37(4): 4791-801, 2016 Apr.

Article en En | MEDLINE | ID: mdl-26520440

Asunto(s)

Curcumina/análogos & derivados; Curcumina/administración & dosificación; Ciclopentanos/administración & dosificación; Quinasa I-kappa B/metabolismo; Proteínas I-kappa B/metabolismo; Neoplasias Gástricas/tratamiento farmacológico; Factor de Transcripción ReIA/biosíntesis; Apoptosis/efectos de los fármacos; Puntos de Control del Ciclo Celular/efectos de los fármacos; Línea Celular Tumoral; Proliferación Celular/efectos de los fármacos; Curcumina/química; Regulación Neoplásica de la Expresión Génica/efectos de los fármacos; Humanos; Quinasa I-kappa B/genética; Proteínas I-kappa B/genética; Inhibidor NF-kappaB alfa; FN-kappa B/genética; Invasividad Neoplásica/genética; Fosforilación/efectos de los fármacos; Proteolisis/efectos de los fármacos; Transducción de Señal/efectos de los fármacos; Neoplasias Gástricas/genética; Neoplasias Gástricas/patología; Factor de Transcripción ReIA/genética; Factor de Necrosis Tumoral alfa/genética

Palabras clave

Anticancer drug; Apoptosis; Curcumin; Gastric cancer; NF-κB; W346

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Gástricas / Proteínas I-kappa B / Curcumina / Ciclopentanos / Quinasa I-kappa B / Factor de Transcripción ReIA Límite: Humans Idioma: En Revista: Tumour Biol Asunto de la revista: NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: China

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