DNA methylation age is associated with mortality in a longitudinal Danish twin study.

Christiansen, Lene; Lenart, Adam; Tan, Qihua; Vaupel, James W; Aviv, Abraham; McGue, Matt; Christensen, Kaare

DNA methylation age is associated with mortality in a longitudinal Danish twin study.

Christiansen, Lene; Lenart, Adam; Tan, Qihua; Vaupel, James W; Aviv, Abraham; McGue, Matt; Christensen, Kaare.

Afiliación

Christiansen L; The Danish Aging Research Center, and The Danish twin Registry, Institute of Public Health, University of Southern Denmark, Odense, Denmark.
Lenart A; Max Planck Odense Center on the Biodemography of Aging, Institute of Public Health, University of Southern Denmark, Odense, Denmark.
Tan Q; The Danish Aging Research Center, and The Danish twin Registry, Institute of Public Health, University of Southern Denmark, Odense, Denmark.
Vaupel JW; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark.
Aviv A; Max Planck Odense Center on the Biodemography of Aging, Institute of Public Health, University of Southern Denmark, Odense, Denmark.
McGue M; Max Planck Institute for Demographic Research, Rostock, Germany.
Christensen K; The Center for Human Development and Aging, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA.

Aging Cell ; 15(1): 149-54, 2016 Feb.

Article en En | MEDLINE | ID: mdl-26594032

Asunto(s)

Envejecimiento/genética; Metilación de ADN/genética; Epigénesis Genética/genética; Mortalidad; Adulto; Anciano; Anciano de 80 o más Años; Dinamarca; Femenino; Humanos; Estudios Longitudinales; Masculino; Persona de Mediana Edad; Datos de Secuencia Molecular

Palabras clave

DNA methylation; biological age; biomarker; epigenetic clock; mortality; twins

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Envejecimiento / Mortalidad / Metilación de ADN / Epigénesis Genética Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Aging Cell Año: 2016 Tipo del documento: Article País de afiliación: Dinamarca

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