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Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells.
Toledo, Chad M; Ding, Yu; Hoellerbauer, Pia; Davis, Ryan J; Basom, Ryan; Girard, Emily J; Lee, Eunjee; Corrin, Philip; Hart, Traver; Bolouri, Hamid; Davison, Jerry; Zhang, Qing; Hardcastle, Justin; Aronow, Bruce J; Plaisier, Christopher L; Baliga, Nitin S; Moffat, Jason; Lin, Qi; Li, Xiao-Nan; Nam, Do-Hyun; Lee, Jeongwu; Pollard, Steven M; Zhu, Jun; Delrow, Jeffery J; Clurman, Bruce E; Olson, James M; Paddison, Patrick J.
Afiliación
  • Toledo CM; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Molecular and Cellular Biology Program, University of Washington, Seattle, WA 98195, USA.
  • Ding Y; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Hoellerbauer P; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Molecular and Cellular Biology Program, University of Washington, Seattle, WA 98195, USA.
  • Davis RJ; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Molecular and Cellular Biology Program, University of Washington, Seattle, WA 98195, USA; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Basom R; Genomics and Bioinformatics Shared Resources, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Girard EJ; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Lee E; Department of Genetics and Genomic Sciences, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Corrin P; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Hart T; Department of Molecular Genetics, University of Toronto and Donnelly Centre, Toronto, ON M5S3E1, Canada; Canadian Institute for Advanced Research, Toronto, ON M5G1Z8, Canada.
  • Bolouri H; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Davison J; Genomics and Bioinformatics Shared Resources, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Zhang Q; Genomics and Bioinformatics Shared Resources, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Hardcastle J; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Aronow BJ; Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.
  • Plaisier CL; Institute for Systems Biology, Seattle, WA 98109, USA.
  • Baliga NS; Institute for Systems Biology, Seattle, WA 98109, USA.
  • Moffat J; Department of Molecular Genetics, University of Toronto and Donnelly Centre, Toronto, ON M5S3E1, Canada; Canadian Institute for Advanced Research, Toronto, ON M5G1Z8, Canada.
  • Lin Q; Brain Tumor Program, Texas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
  • Li XN; Brain Tumor Program, Texas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
  • Nam DH; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul 135-710, Korea.
  • Lee J; Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44192, USA.
  • Pollard SM; Edinburgh CRUK Cancer Research Centre and MRC Centre for Regenerative Medicine, The University of Edinburgh, Edinburgh EH16 4UU, UK.
  • Zhu J; Department of Genetics and Genomic Sciences, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Delrow JJ; Genomics and Bioinformatics Shared Resources, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Clurman BE; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Olson JM; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. Electronic address: jolson@fredhutch.org.
  • Paddison PJ; Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Molecular and Cellular Biology Program, University of Washington, Seattle, WA 98195, USA. Electronic address: paddison@fredhutch.org.
Cell Rep ; 13(11): 2425-2439, 2015 Dec 22.
Article en En | MEDLINE | ID: mdl-26673326
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Proteínas Tirosina Quinasas / Proteínas Nucleares / Genoma Humano / Proteínas Serina-Treonina Quinasas / Proteínas de Ciclo Celular / Sistemas CRISPR-Cas / Proteínas de la Membrana Tipo de estudio: Prognostic_studies Idioma: En Revista: Cell Rep Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Proteínas Tirosina Quinasas / Proteínas Nucleares / Genoma Humano / Proteínas Serina-Treonina Quinasas / Proteínas de Ciclo Celular / Sistemas CRISPR-Cas / Proteínas de la Membrana Tipo de estudio: Prognostic_studies Idioma: En Revista: Cell Rep Año: 2015 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos