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Epithelial-Mesenchymal Transition and Immune Evasion during Lung Cancer Progression: The Chicken or the Egg?
Datar, Ila; Schalper, Kurt A.
Afiliación
  • Datar I; Department of Pathology, Yale School of Medicine, New Haven, Connecticut. Translational Immuno-oncology Laboratory, Yale Cancer Center, New Haven, Connecticut.
  • Schalper KA; Department of Pathology, Yale School of Medicine, New Haven, Connecticut. Translational Immuno-oncology Laboratory, Yale Cancer Center, New Haven, Connecticut. Medical Oncology, Yale School of Medicine and Yale Cancer Center, New Haven, Connecticut. kurt.schalper@yale.edu.
Clin Cancer Res ; 22(14): 3422-4, 2016 07 15.
Article en En | MEDLINE | ID: mdl-27076625
Epithelial-mesenchymal transition (EMT) is a complex process involved in metastasis. Immune evasion is required for tumor progression and is characterized by an ineffective antitumor immune response and upregulation of immune-suppressive signals. The coexistence of EMT and adaptive immune evasion opens the possibility of a mechanistic link between these processes. Clin Cancer Res; 22(14); 3422-4. ©2016 AACRSee related article by Lou et al., p. 3630.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Evasión Inmune / Transición Epitelial-Mesenquimal / Neoplasias Pulmonares Límite: Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Evasión Inmune / Transición Epitelial-Mesenquimal / Neoplasias Pulmonares Límite: Humans Idioma: En Revista: Clin Cancer Res Asunto de la revista: NEOPLASIAS Año: 2016 Tipo del documento: Article Pais de publicación: Estados Unidos